Hazarders of Smoking and <i>Helicobacter pylori</i> Infection on Gastric Mucosa among Egyptian Patients with Dyspepsia

Background: Smoking is hazardous to almost any organ in the body and has a harmful effect on gastric mucosa. Objective: The main goal of this study was evaluate synergistic smoking H. pylori infection mucosal among dyspeptic Egyptian patients. Patients Methods: A cross-sectional conducted 240 consecutive patients with dyspepsia who underwent upper endoscopy histopathological examination biopsies at Zagazig Tanta University Hospital pylori-positivity assessment by stool antigen rapid urease test. Results: There were 60 smoker 180 non-smoker Erosive gastritis more prevalent than (46.7% versus 15.6%, p = 0.00). In pylori-positive (36.7% all patients), smokers non-smokers development intestinal metaplasia (20% 0%, 0.003), erosive (80% 30%, 0.00), glandular atrophy 0.003) reactive gastropathy 0.003). Conclusions: This revealed that may increase prevalence having metaplasia, gastritis,